Skin Cyle Part 2 A skin cycle can vary with each individual and is affected by such factors as age, hormones, skin condition/health and stress. On average a skin cycle is 5-6 weeks. At the age of 19-21,the process can take 14-21 days compared to a middle-aged adult where it is estimated to be 28 days. As we grow older, this skin cycle slows to about 45-60 days in our 40’s and 50’s. It can further slow to about 60-90 days in our 50’s and 60’s.