Never Give Up: What does it means to never give up? What it means to never give up, it means to believe in yourself, your dreams, and your hopes. When you believe in yourself, you believe that you can accomplish anything that you want to do in your life. It’s important to know that whatever goals you want to achieve in life, will have difficult challenges. But you can face any difficult challenges as long as you believe yourself, pull that motivation on the inside of you, and never give up.