After 3+ years of symptoms, i finally found the protocol that works for me—which i had been fighting for (and told i couldn’t get) that whole time: spironolactone + metformin + cyclic progesterone. In that period i developed hidradenitis suppurativa, insulin resistance, and hirsutism, gained a substantial amount of weight, lost more than half of my hair (it hasn’t returned), and dealt with breast atrophy. It happened swiftly and brutally during the early parts of COVID.